Organooxygen compounds
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Medchemexpress LLC 14-Deoxy-11,12-didehydroandrographolide | 42895-58-9 | MFCD07778081 | 332.43 | 100 MG
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. It inhibits NF-κB activation.
- An analogue of Andrographolide.
- Inhibits NF-κB activation.
- Reduces ovalbumin (OVA)-induced inflammatory cell recruitment into bronchoalveolar lavage (BAL) fluid, IL-4, IL-5, IL-13, eotaxin production, serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion, mast cell degranulation, and airway hyper-responsiveness (AHR) in a mouse asthma model.
- At 1 mg/kg, it dramatically reduces resistance (Rl) and restores Cdyn in OVA-challenged mice in response to methacholine.
- Appearance: Solid.
- Color: White to light yellow.
- Purity: 99.93%.
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Medchemexpress LLC 6A-azido-6A-deoxy-β-cyclodextrin | 98169-85-8 | MFCD05864973 | 98.0% | 1160.00 g·mol⁻1 | C42H69N3O34 | 100 MG
6A-Azido-6A-deoxy-β-cyclodextrin is an azide-functionalized β-cyclodextrin supplied as a solid reagent for click chemistry and bioconjugation. It offers a single azide handle on the cyclodextrin scaffold for site-selective conjugation and host-guest chemistry studies.
- Azide functional group suitable for copper-catalyzed azide-alkyne cycloaddition.
- High purity (98.0%) for reproducible synthetic and analytical work.
- Good solubility in DMSO (≈125 mg/mL) for stock solution preparation.
- Stable as powder at -20°C for long-term storage and in solution at -80°C for months.
- Useful for bioconjugation, drug-delivery, and supramolecular chemistry applications.
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